Xianjun Zhu Selected Research

Familial Exudative Vitreoretinopathies

11/2023	Defective EMC1 drives abnormal retinal angiogenesis via Wnt/β-catenin signaling and may be associated with the pathogenesis of familial exudative vitreoretinopathy.
1/2022	CTNND1 variants cause familial exudative vitreoretinopathy through the Wnt/cadherin axis.
6/2021	Whole-Exome Sequencing Reveals Novel TSPAN12 Variants in Autosomal Dominant Familial Exudative Vitreoretinopathy.
5/2021	Whole-Exome Sequencing Identified DLG1 as a Candidate Gene for Familial Exudative Vitreoretinopathy.
1/2021	Catenin α 1 mutations cause familial exudative vitreoretinopathy by overactivating Norrin/β-catenin signaling.
2/2020	Identification of Novel Mutations in the FZD4 and NDP Genes in Patients with Familial Exudative Vitreoretinopathy in South India.
1/2020	Exome sequencing revealed Notch ligand JAG1 as a novel candidate gene for familial exudative vitreoretinopathy.
7/2016	Whole Exome Sequencing Analysis Identifies Mutations in LRP5 in Indian Families with Familial Exudative Vitreoretinopathy.

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Xianjun Zhu Research Topics

Disease

9	Neoplasms (Cancer) 03/2024 - 05/2015
8	Familial Exudative Vitreoretinopathies 11/2023 - 07/2016
7	Retinitis Pigmentosa (Pigmentary Retinopathy) 01/2020 - 08/2015
4	Gliosis 03/2024 - 01/2018
4	Vascular Diseases (Vascular Disease) 05/2021 - 01/2020
3	Hepatocellular Carcinoma (Hepatoma) 12/2023 - 12/2020
3	Glaucoma 10/2021 - 04/2012
3	Blindness (Hysterical Blindness) 01/2021 - 01/2020
3	Neoplasm Metastasis (Metastasis) 01/2020 - 08/2015
3	Colorectal Neoplasms (Colorectal Cancer) 08/2017 - 05/2015
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 01/2012
2	Aneurysm (Aneurysms) 11/2021 - 01/2019
2	Hyperglycemia 01/2021 - 01/2014
2	Colonic Neoplasms (Colon Cancer) 01/2021 - 08/2015
1	Neurodevelopmental Disorders 03/2024
1	Late-Onset Retinal Degeneration 01/2022
1	Non-alcoholic Fatty Liver Disease 01/2022
1	Obesity 01/2021
1	Insulin Resistance 01/2021
1	Hyperinsulinism (Hyperinsulinemia) 01/2021
1	Albuminuria 01/2021
1	Glucose Intolerance 01/2021
1	Ischemia 06/2020
1	Ocular Hypertension (Glaucoma, Suspect) 06/2020
1	Reperfusion Injury 06/2020
1	Lung Neoplasms (Lung Cancer) 05/2020
1	Carcinogenesis 05/2020
1	Retinal Degeneration 01/2020
1	Vitelliform Macular Dystrophy 01/2020
1	Disease Progression 01/2019
1	progressive familial intrahepatic 1 Cholestasis 12/2017
1	Intrahepatic Cholestasis 12/2017
1	Carcinoma (Carcinomatosis) 08/2017
1	Stargardt Disease 01/2014
1	Diabetic Ketoacidosis (Ketoacidosis, Diabetic) 01/2014

Drug/Important Bio-Agent (IBA)

13	Retinaldehyde (Retinal)IBA 11/2023 - 07/2016
9	Proteins (Proteins, Gene)FDA Link 03/2024 - 05/2015
3	6-methyladenineIBA 12/2023 - 01/2022
3	Glial Fibrillary Acidic ProteinIBA 01/2020 - 01/2018
2	Rhodopsin (Visual Purple)IBA 03/2024 - 01/2020
2	CateninsIBA 11/2023 - 01/2021
2	MicroRNAs (MicroRNA)IBA 01/2022 - 01/2017
2	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2021 - 09/2020
2	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA 01/2018 - 01/2018
1	LipidsIBA 03/2024
1	GlycolipidsIBA 12/2023
1	IronIBA 12/2023
1	DNA (Deoxyribonucleic Acid)IBA 11/2023
1	Cadherins (E-Cadherin)IBA 01/2022
1	RNA (Ribonucleic Acid)IBA 01/2022
1	Acetylcysteine (Siran)FDA LinkGeneric 10/2021
1	Neuroprotective AgentsIBA 10/2021
1	Hydroxyl RadicalIBA 10/2021
1	Insulin (Novolin)FDA Link 01/2021
1	PhosphatidylserinesIBA 01/2021
1	GTP-Binding Proteins (G-Protein)IBA 12/2020
1	Estrogen Receptor alphaIBA 12/2020
1	1-phenyl-3,3-dimethyltriazene (PDT)IBA 09/2020
1	TransferasesIBA 06/2020
1	ProdrugsIBA 05/2020
1	taxifolinIBA 05/2020
1	LigandsIBA 01/2020
1	Proteoglycans (Proteoglycan)IBA 01/2020
1	StaurosporineIBA 01/2020
1	Therapeutic UsesIBA 01/2019
1	c-Mer Tyrosine KinaseIBA 03/2018
1	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 01/2018
1	Adenosine Triphosphatases (ATPase)IBA 12/2017
1	Bile Acids and Salts (Bile Acids)IBA 12/2017
1	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 12/2017
1	Fatty Acid Synthases (Fatty Acid Synthase)IBA 08/2017
1	Fatty Acids (Saturated Fatty Acids)IBA 08/2017
1	4,4- difluoro- 4- bora- 3a,4a- diaza- s- indacene (BODIPY)IBA 08/2017
1	Complement System Proteins (Complement)IBA 01/2017
1	RTKI cpdIBA 01/2017
1	CCG 1423IBA 01/2017
1	Receptor for Advanced Glycation End ProductsIBA 08/2015
1	CollagenIBA 05/2015
1	Messenger RNA (mRNA)IBA 05/2015
1	Staphylococcal Protein A (Protein A)IBA 01/2014
1	KetonesIBA 01/2014
1	Adenosine Triphosphate (ATP)IBA 01/2014
1	AcidsIBA 01/2014
1	Glucose (Dextrose)FDA LinkGeneric 01/2014
1	Endothelin-2IBA 04/2012
1	Phospholipid Transfer ProteinsIBA 01/2012

Therapy/Procedure

4	Therapeutics 10/2021 - 08/2015
1	Lasers (Laser) 08/2017
1	Radiotherapy 04/2012